Fc epsilon R1-mediated tyrosine phosphorylation of multiple proteins, including phospholipase C gamma 1 and the receptor beta gamma 2 complex, in RBL-2H3 rat basophilic leukemia cells.

In basophils, mast cells, and the RBL-2H3 tumor mast cell line, cross-linking the high-affinity immunoglobulin E receptor (Fc epsilon R1) stimulates a series of responses, particularly the activation of phospholipase C (PLC), that lead to allergic and other immediate hypersensitivity reactions. The...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Li, W, Deanin, G G, Margolis, B, Schlessinger, J, Oliver, J M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364532/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1535686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.7.3176-3182.1992
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