The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein.

The v- and c-Rel oncoproteins bind to oligonucleotides containing kappa B motifs, form heterodimers with other members of the Rel family, and modulate expression of genes linked to kappa B motifs. Here, we report that the RxxRxRxxC motif conserved in all Rel/kappa B family proteins is absolutely req...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Kumar, S, Rabson, A B, Gélinas, C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.7.3094-3106.1992
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