The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers.
In most cells, proteins belonging to the Rel/NF-kappa B family of transcription factors are held in inactive form in the cytoplasm by an inhibitor protein, I kappa B alpha. Stimulation of the cells leads to degradation of the inhibitor and transit of active DNA-binding Rel/NF-kappa B dimers to the n...
Na minha lista:
| Udgivet i: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1995
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231969/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.872 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|