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Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives

Hemophilia is a bleeding disorder that afflicts about 1 in 5000 males. Treatment relies upon replacement of the deficient factor, and response to treatment both in clinical research and practice is based upon subjective parameters such as pain and joint mobility. Existing laboratory assays quantify...

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Autors principals: Young, Guy, Sørensen, Benny, Dargaud, Yesim, Negrier, Claude, Brummel-Ziedins, Kathleen, Key, Nigel S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645054/
https://ncbi.nlm.nih.gov/pubmed/23319573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-378935
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