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Thrombin generation and fibrin clot formation under hypothermic conditions: an in vitro evaluation of tissue factor initiated whole blood coagulation

BACKGROUND: Despite trauma-induced hypothermic coagulopathy being familiar in the clinical setting, empirical experimentation concerning this phenomenon is lacking. In this study we investigated the effects of hypothermia on thrombin generation, clot formation and global hemostatic functions in an i...

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Bibliographic Details
Published in:J Crit Care
Main Authors: Whelihan, Matthew F., Kiankhooy, Armin, Brummel-Ziedins, Kathleen
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355959/
https://ncbi.nlm.nih.gov/pubmed/24331944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcrc.2013.10.010
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