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Application of highly sensitive UPLC-MS to determine biodistribution at tracer doses: Validation with the 5-HT(1A) Ligand [(18)F]FPWAY
High sensitivity and high resolution LC/MS instrumentation has been applied in PET radiopharmaceutical development to provide quantitative measurement of the mass of radiotracers extracted from tissues of rats. We employed the highly sensitive Waters Q-TOF premier MS coupled with an Acquity UPLC sys...
Tallennettuna:
Päätekijät: | , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2009
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644855/ https://ncbi.nlm.nih.gov/pubmed/19423006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2009.01.002 |
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