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Application of highly sensitive UPLC-MS to determine biodistribution at tracer doses: Validation with the 5-HT(1A) Ligand [(18)F]FPWAY

High sensitivity and high resolution LC/MS instrumentation has been applied in PET radiopharmaceutical development to provide quantitative measurement of the mass of radiotracers extracted from tissues of rats. We employed the highly sensitive Waters Q-TOF premier MS coupled with an Acquity UPLC sys...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ma, Ying, Lang, Lixin, Reyes, Larry, Tokugawa, Joji, Jagoda, Elaine M, Kiesewetter, Dale O.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644855/
https://ncbi.nlm.nih.gov/pubmed/19423006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2009.01.002
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