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Local Endocrine, Paracrine and Redox Signaling Networks Impact Estrogen and Androgen Crosstalk in the Prostate Cancer Microenvironment

Androgen receptor (AR) signaling is essential for the initial development and progression of prostate cancer (PCa) as well as the growth and survival of castration-resistant tumors. However, AR action may be opposed by estrogen receptor beta (ERβ) that responds to androgen metabolites produced in th...

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Detalhes bibliográficos
Main Authors: Grubisha, Melanie J., DeFranco, Donald B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644803/
https://ncbi.nlm.nih.gov/pubmed/23380371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2013.01.005
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