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Local Endocrine, Paracrine and Redox Signaling Networks Impact Estrogen and Androgen Crosstalk in the Prostate Cancer Microenvironment

Androgen receptor (AR) signaling is essential for the initial development and progression of prostate cancer (PCa) as well as the growth and survival of castration-resistant tumors. However, AR action may be opposed by estrogen receptor beta (ERβ) that responds to androgen metabolites produced in th...

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Bibliografske podrobnosti
Main Authors: Grubisha, Melanie J., DeFranco, Donald B.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644803/
https://ncbi.nlm.nih.gov/pubmed/23380371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2013.01.005
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