Activation of a mammalian origin of replication by chromosomal rearrangement.
The methotrexate-resistant Chinese hamster cell line DC3F/A3-4K (A3/4K) contains at least two prominent dihydrofolate reductase amplicon types. The type I amplicons, constituting approximately 80% of the total, are at least 650 kb in length, but the endpoints have not yet been characterized. The typ...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1992
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1588972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2804-2812.1992 |
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