HIV-1 Vpu affects the anterograde transport and the glycosylation pattern of NTB-A

HIV-1 Vpu induces downregulation of cell surface NTB-A to evade lysis of HIV-1 infected cells by NK cells. Here we show that Vpu affects the anterograde transport and the glycosylation pattern of NTB-A by a mechanism that is distinct from the Vpu induced downregulation of CD4 and tetherin. In the pr...

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Main Authors: Bolduan, Sebastian, Hubel, Philipp, Reif, Tatjana, Lodermeyer, Veronika, Höhne, Kristin, Fritz, Joëlle V., Sauter, Daniel, Kirchhoff, Frank, Fackler, Oliver T., Schindler, Michael, Schubert, Ulrich
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644704/
https://ncbi.nlm.nih.gov/pubmed/23528733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.02.021
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