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Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV
The human immunodeficiency virus type 1 (HIV-1) protein Vpu is encoded exclusively by HIV-1 and related simian immunodeficiency viruses (SIVs). The transmembrane domain of the protein has dual functions: it counteracts the human restriction factor tetherin and forms a cation channel. Since these two...
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Publicado no: | Viruses |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5192386/ https://ncbi.nlm.nih.gov/pubmed/27916968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8120325 |
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