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Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV

The human immunodeficiency virus type 1 (HIV-1) protein Vpu is encoded exclusively by HIV-1 and related simian immunodeficiency viruses (SIVs). The transmembrane domain of the protein has dual functions: it counteracts the human restriction factor tetherin and forms a cation channel. Since these two...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Greiner, Timo, Bolduan, Sebastian, Hertel, Brigitte, Groß, Christine, Hamacher, Kay, Schubert, Ulrich, Moroni, Anna, Thiel, Gerhard
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192386/
https://ncbi.nlm.nih.gov/pubmed/27916968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8120325
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