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Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck.

To understand the mechanism(s) by which p56lck participates in T-cell receptor (TCR) signalling, we have examined the effects of mutations in known regulatory domains of p56lck on the ability of F505 p56lck to enhance the responsiveness of an antigen-specific murine T-cell hybridoma. A mutation of t...

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Библиографические подробности
Главные авторы: Caron, L, Abraham, N, Pawson, T, Veillette, A
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC364466/
https://ncbi.nlm.nih.gov/pubmed/1375326
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