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Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS
Genetic mapping of complex diseases to date depends on variations inside or close to the genes that perturb their activities. A strong body of evidence suggests that changes in gene expression play a key role in complex diseases and that numerous loci perturb gene expression in trans. The informatio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644637/ https://ncbi.nlm.nih.gov/pubmed/23643380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.03.022 |
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