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Point mutations in the Drosophila hairy gene demonstrate in vivo requirements for basic, helix-loop-helix, and WRPW domains.

The Drosophila pair-rule gene, hairy (h), encodes a nuclear basic helix-loop-helix (bHLH) protein that regulates embryonic segmentation and adult bristle patterning. In both cases, the h protein behaves as a transcriptional repressor. In this study, we determined the molecular nature of 12 h alleles...

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Publicat a:Mol Cell Biol
Autors principals: Wainwright, S M, Ish-Horowicz, D
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1588951/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2475-2483.1992
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