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Enzymes involved in L-carnitine biosynthesis are expressed by small intestinal enterocytes in mice: Implications for gut health

BACKGROUND: Carnitine is essential for mitochondrial β-oxidation of long-chain fatty acids. Deficiency of carnitine leads to severe gut atrophy, ulceration and inflammation in animal models of carnitine deficiency. Genetic studies in large populations have linked mutations in the carnitine transport...

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Detalhes bibliográficos
Main Authors: Shekhawat, Prem S, Sonne, Srinivas, Carter, A Lee, Matern, Dietrich, Ganapathy, Vadivel
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644392/
https://ncbi.nlm.nih.gov/pubmed/22999781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crohns.2012.08.011
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