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Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+)

L-Carnitine is absorbed in the intestinal tract via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+). Loss-of-function mutations in OCTN2 may be associated with inflammatory bowel disease (IBD), suggesting a role for carnitine in intestinal/colonic health. In contrast, ATB(0,+...

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Hlavní autoři: Srinivas, Sonne R., Prasad, Puttur D., Umapathy, Nagavedi S., Ganapathy, Vadivel, Shekhawat, Prem S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583010/
https://ncbi.nlm.nih.gov/pubmed/17855766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00233.2007
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