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Microbe-dependent CD11b(+) IgA(+) plasma cells mediate robust early-phase intestinal IgA responses in mice

Intestinal plasma cells predominantly produce immunoglobulin (Ig) A, however, their functional diversity remains poorly characterized. Here we show that murine intestinal IgA plasma cells can be newly classified into two populations on the basis of CD11b expression, which cannot be discriminated by...

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Detalhes bibliográficos
Main Authors: Kunisawa, Jun, Gohda, Masashi, Hashimoto, Eri, Ishikawa, Izumi, Higuchi, Morio, Suzuki, Yuji, Goto, Yoshiyuki, Panea, Casandra, Ivanov, Ivaylo I., Sumiya, Risa, Aayam, Lamichhane, Wake, Taichi, Tajiri, So, Kurashima, Yosuke, Shikata, Shiori, Akira, Shizuo, Takeda, Kiyoshi, Kiyono, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644083/
https://ncbi.nlm.nih.gov/pubmed/23612313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2718
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