Structural elements of ornithine decarboxylase required for intracellular degradation and polyamine-dependent regulation.

Mammalian ornithine decarboxylase (ODC), a key enzyme in polyamine biosynthesis, is rapidly degraded in cells, an attribute important to the regulation of its activity. Mutant and chimeric ODCs were created to determine the structural requirements for two modes of proteolysis. Constitutive degradati...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ghoda, L, Sidney, D, Macrae, M, Coffino, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569947/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.2178-2185.1992
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