Structural elements of ornithine decarboxylase required for intracellular degradation and polyamine-dependent regulation.

Mammalian ornithine decarboxylase (ODC), a key enzyme in polyamine biosynthesis, is rapidly degraded in cells, an attribute important to the regulation of its activity. Mutant and chimeric ODCs were created to determine the structural requirements for two modes of proteolysis. Constitutive degradati...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Ghoda, L, Sidney, D, Macrae, M, Coffino, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569947/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.2178-2185.1992
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