7,8-dihydroxyflavone exhibits therapeutic efficacy in a mouse model of Rett syndrome

Rett syndrome (RTT), caused by mutations in the methyl-CpG binding protein 2 gene (MECP2), is a debilitating autism spectrum developmental disorder predominantly affecting females. Mecp2 mutant mice have reduced levels of brain-derived neurotrophic factor (BDNF) in the brain; conditional deletion an...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Johnson, Rebecca A., Lam, Maxine, Punzo, Antonio M., Li, Hongda, Lin, Benjamin R., Ye, Keqiang, Mitchell, Gordon S., Chang, Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2012
Materias:
Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643819/
https://ncbi.nlm.nih.gov/pubmed/22194327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01361.2011
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares