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Dissection of cell cycle–dependent dynamics of Dnmt1 by FRAP and diffusion-coupled modeling
DNA methyltransferase 1 (Dnmt1) reestablishes methylation of hemimethylated CpG sites generated during DNA replication in mammalian cells. Two subdomains, the proliferating cell nuclear antigen (PCNA)-binding domain (PBD) and the targeting sequence (TS) domain, target Dnmt1 to the replication sites...
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Päätekijät: | , , , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Oxford University Press
2013
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643600/ https://ncbi.nlm.nih.gov/pubmed/23535145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt191 |
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