Corticospinal Motor Neurons and Related Subcerebral Projection Neurons Undergo Early and Specific Neurodegeneration in hSOD1(G93A) Transgenic ALS Mice

Amyotrophic lateral sclerosis (ALS) is characterized by predominant vulnerability and central degeneration of both corticospinal/corticobulbar motor neurons (CSMN; “upper motor neurons”) in cerebral cortex, and spinal/bulbar motor neurons (SMN; “lower motor neurons”) in spinal cord and brainstem. In...

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Main Authors: Özdinler, P. Hande, Benn, Susanna, Yamamoto, Ted H., Güzel, Mine, Brown, Robert H., Macklis, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643523/
https://ncbi.nlm.nih.gov/pubmed/21411657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4184-10.2011
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