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Neutrophil Protease Inhibition Reduces Neuromyelitis Optica–Immunoglobulin G–Induced Damage in Mouse Brain
OBJECTIVE: Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system associated with pathogenic autoantibodies against the astrocyte water channel protein aquaporin-4 (AQP4). The presence of neutrophils is a characteristic feature in NMO lesions in humans. Neu...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643520/ https://ncbi.nlm.nih.gov/pubmed/22374891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22686 |
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