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β2 Integrin-mediated Cell-Cell Contact Transfers Active Myeloperoxidase from Neutrophils to Endothelial Cells

Atherosclerosis and vasculitis both feature inflammation mediated by neutrophil-endothelial cell (EC) contact. Neutrophil myeloperoxidase (MPO) can disrupt normal EC function, although the mechanism(s) by which MPO is transferred to ECs are unknown. We tested the hypothesis that close, β2 integrin-d...

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Bibliographische Detailangaben
Hauptverfasser: Jerke, Uwe, Rolle, Susanne, Purfürst, Bettina, Luft, Friedrich C., Nauseef, William M., Kettritz, Ralph
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642334/
https://ncbi.nlm.nih.gov/pubmed/23532856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434613
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