β2 Integrin-mediated Cell-Cell Contact Transfers Active Myeloperoxidase from Neutrophils to Endothelial Cells

Atherosclerosis and vasculitis both feature inflammation mediated by neutrophil-endothelial cell (EC) contact. Neutrophil myeloperoxidase (MPO) can disrupt normal EC function, although the mechanism(s) by which MPO is transferred to ECs are unknown. We tested the hypothesis that close, β2 integrin-d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jerke, Uwe, Rolle, Susanne, Purfürst, Bettina, Luft, Friedrich C., Nauseef, William M., Kettritz, Ralph
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642334/
https://ncbi.nlm.nih.gov/pubmed/23532856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434613
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