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Identification of amino acids in human colipase that mediate adsorption to lipid emulsions and mixed micelles

The adsorption of colipase is essential for pancreatic triglyceride lipase activity and efficient dietary fat digestion. Yet, little is known about which specific amino acids in the hydrophobic surface of colipase influence adsorption. In this study, we systematically substituted alanine or tryptoph...

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Detalhes bibliográficos
Main Authors: Ross, Leah E., Xiao, Xunjun, Lowe, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642234/
https://ncbi.nlm.nih.gov/pubmed/23470256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2013.02.009
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