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Identification of amino acids in human colipase that mediate adsorption to lipid emulsions and mixed micelles

The adsorption of colipase is essential for pancreatic triglyceride lipase activity and efficient dietary fat digestion. Yet, little is known about which specific amino acids in the hydrophobic surface of colipase influence adsorption. In this study, we systematically substituted alanine or tryptoph...

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Main Authors: Ross, Leah E., Xiao, Xunjun, Lowe, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642234/
https://ncbi.nlm.nih.gov/pubmed/23470256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2013.02.009
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