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The manner in which DNA is packaged with TFAM has an impact on transcription activation and inhibition

For successful mitochondrial transgene expression, an optimal packaging exogenous DNA is an important issue. We report herein on the effects of DNA packaged with mitochondrial transcription factor A (TFAM), which packages mitochondrial DNA (mtDNA), on the transcription process. Our initial findings...

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Detalhes bibliográficos
Main Authors: Furukawa, Ryo, Yamada, Yuma, Matsushima, Yuichi, Goto, Yu-ichi, Harashima, Hideyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642137/
https://ncbi.nlm.nih.gov/pubmed/23650593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2012.06.001
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