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Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation
TFAM is a DNA binding protein that activates transcription at the two major promoters of mitochondrial DNA — the light strand promoter (LSP) and heavy strand promoter 1 (HSP1). Equally important, it coats and packages the mitochondrial genome. TFAM has been shown to impose a U-turn on LSP DNA, but w...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936014/ https://ncbi.nlm.nih.gov/pubmed/24435062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4077 |
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