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Distinguishable In Vitro Binding Mode of Monomeric TRBP and Dimeric PACT with siRNA
RNA interference (RNAi) is an evolutionally conserved posttranscriptional gene-silencing mechanism whereby small interfering RNA (siRNA) triggers sequence-specific cleavage of its cognate mRNA. Dicer, Argonaute (Ago), and either TAR-RNA binding protein (TRBP) or a protein activator of PKR (PACT) are...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642127/ https://ncbi.nlm.nih.gov/pubmed/23658827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063434 |
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