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Attachment Site Selection and Identity in Bxb1 Serine Integrase-Mediated Site-Specific Recombination

Phage-encoded serine integrases mediate directionally regulated site-specific recombination between short attP and attB DNA sites without host factor requirements. These features make them attractive for genome engineering and synthetic genetics, although the basis for DNA site selection is poorly u...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Singh, Shweta, Ghosh, Pallavi, Hatfull, Graham F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642061/
https://ncbi.nlm.nih.gov/pubmed/23658531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003490
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