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Successive and Targeted DNA Integrations in the Drosophila Genome by Bxb1 and φC31 Integrases

At present φC31 is the only phage integrase system available for directionally regulated site-specific DNA integration in the Drosophila genome. Here we report that mycobacteriophage Bxb1 integrase also mediates targeted DNA integration in Drosophila with high specificity and efficiency. By alternat...

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Библиографические подробности
Главные авторы: Huang, Juan, Ghosh, Pallavi, Hatfull, Graham F, Hong, Yang
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176133/
https://ncbi.nlm.nih.gov/pubmed/21652525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.129247
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