Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria

BACKGROUND: Human cerebral malaria (HCM) is a life-threatening complication caused by Plasmodium falciparum infection that continues to be a major global health problem despite optimal anti-malarial treatment. In the experimental model of cerebral malaria (ECM) by Plasmodium berghei ANKA, bolus admi...

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Detalhes bibliográficos
Main Authors: Martins, Yuri C, Clemmer, Leah, Orjuela-Sánchez, Pamela, Zanini, Graziela M, Ong, Peng Kai, Frangos, John A, Carvalho, Leonardo JM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642006/
https://ncbi.nlm.nih.gov/pubmed/23617605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-138
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