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Probing the recognition surface of a DNA triplex: Binding studies with intercalator-neomycin conjugates

Thermodynamic studies on the interactions between intercalator-neomycin conjugates and a DNA polynucleotide triplex [poly(dA)•2poly(dT)] were conducted. To draw a complete picture of such interactions, naphthalenedimide-neomycin (3) and anthraquinone-neomycin (4) were synthesized and used together w...

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Библиографические подробности
Главные авторы: Xue, Liang, Xi, Hongjuan, Kumar, Sunil, Gray, David, Davis, Erik, Hamilton, Paris, Skirba, Michael, Arya, Dev P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641831/
https://ncbi.nlm.nih.gov/pubmed/20499878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100071j
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