Nalaganje...
Altered expression of protein kinase C, lck, and CD45 in a 12-O-tetradecanoylphorbol-13-acetate-dependent leukemic T-cell variant that expresses a high level of interleukin-2 receptor.
The compound 12-O-tetradecanoylphorbol-13-acetate (TPA) is extremely toxic to the P13 subclone of the Jurkat human T-cell leukemia line. By selecting for growth in the presence of TPA, we have isolated two TPA-resistant variants of these cells, P13-50 and P13-5/A8. Studies of protein kinase C (PKC)...
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Main Authors: | , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
1992
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC364134/ https://ncbi.nlm.nih.gov/pubmed/1530879 |
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