Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells

Colorectal cancer is the third leading cause of cancer-related mortality in the world; the main cause of death of colorectal cancer is hepatic metastases, which can be treated with hyperthermia using isolated hepatic perfusion (IHP). In this study, we report that mild hyperthermia potently reduced c...

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Hauptverfasser: Song, X, Kim, S-Y, Zhou, Z, Lagasse, E, Kwon, Y T, Lee, Y J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641327/
https://ncbi.nlm.nih.gov/pubmed/23559011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.104
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