Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells

Colorectal cancer is the third leading cause of cancer-related mortality in the world; the main cause of death of colorectal cancer is hepatic metastases, which can be treated with hyperthermia using isolated hepatic perfusion (IHP). In this study, we report that mild hyperthermia potently reduced c...

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Autores principales: Song, X, Kim, S-Y, Zhou, Z, Lagasse, E, Kwon, Y T, Lee, Y J
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641327/
https://ncbi.nlm.nih.gov/pubmed/23559011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.104
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