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Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery

BACKGROUND: Conventional treatment for locally advanced rectal cancer usually combines neoadjuvant radiochemotherapy and surgery. Until recently, there have been limited predictive factors (clinical or biological) for rectal tumor response to conventional treatment. KRAS, BRAF and PIK3CA mutations a...

詳細記述

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書誌詳細
主要な著者: Derbel, Olfa, Wang, Qing, Desseigne, Françoise, Rivoire, Michel, Meeus, Pierre, Peyrat, Patrice, Stella, Mattia, Martel-Lafay, Isabelle, Lemaistre, Anne-Isabelle, de La Fouchardière, Christelle
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640970/
https://ncbi.nlm.nih.gov/pubmed/23617638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-200
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