Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery

BACKGROUND: Conventional treatment for locally advanced rectal cancer usually combines neoadjuvant radiochemotherapy and surgery. Until recently, there have been limited predictive factors (clinical or biological) for rectal tumor response to conventional treatment. KRAS, BRAF and PIK3CA mutations a...

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Detalhes bibliográficos
Main Authors: Derbel, Olfa, Wang, Qing, Desseigne, Françoise, Rivoire, Michel, Meeus, Pierre, Peyrat, Patrice, Stella, Mattia, Martel-Lafay, Isabelle, Lemaistre, Anne-Isabelle, de La Fouchardière, Christelle
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640970/
https://ncbi.nlm.nih.gov/pubmed/23617638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-200
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