Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis characterized by entry of activated T cells and antigen presenting cells into the central nervous system and subsequent autoimmune destruction of nerve myelin. Previous studies revealed that non-sele...

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Detalhes bibliográficos
Main Authors: Kamboj, Amit, Lu, Ping, Cossoy, Michael B, Stobart, Jillian L, Dolhun, Brian A, Kauppinen, Tiina M, de Murcia, Gilbert, Anderson, Christopher M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640934/
https://ncbi.nlm.nih.gov/pubmed/23607899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-49
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