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An SOD mimic protects NADP(+)-dependent isocitrate dehydrogenase against oxidative inactivation

The isocitrate dehydrogenases (ICDs) catalyse the oxidative decarboxylation of isocitrate to alpha-ketoglutarate and can use either NAD(+) or NADP(+) as a cofactor. Recent studies demonstrate that the NADP(+)-dependent isocitrate dehydrogenase, as a source of electrons for cellular antioxidants, is...

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Hlavní autoři: Batinic-Haberle, Ines, Benov, Ludmil T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640869/
https://ncbi.nlm.nih.gov/pubmed/18608518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10715760802209639
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