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Reconstitution of the early steps of gliotoxin biosynthesis in Aspergillus nidulans reveals the role of the monooxygenase GliC

The gliotoxin, a member of the epipolythiodioxopiperazine (ETP), has received considerable attention from the scientific community for its wide range of biological activity. Despite the identification of gliotoxin cluster, however, the sequence of steps in the gliotoxin biosynthesis has remained elu...

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Detalhes bibliográficos
Main Authors: Chang, Shu-Lin, Chiang, Yi-Ming, Yeh, Hsu-Hua, Wu, Tung-Kung, Wang, Clay C. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640825/
https://ncbi.nlm.nih.gov/pubmed/23434416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.01.099
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