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Persistent LCMV infection is controlled by blockade of type 1 interferon signaling
During persistent viral infections, chronic immune activation, negative immune regulator expression, an elevated interferon signature and lymphoid tissue destruction correlate with disease progression. Here, we demonstrate that blockade of type 1 interferon (IFN-I) signaling using a type 1 interfero...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640797/ https://ncbi.nlm.nih.gov/pubmed/23580529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1235214 |
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