Lipopolysaccharide-induced NF-kappa B activation in mouse 70Z/3 pre-B lymphocytes is inhibited by mevinolin and 5'-methylthioadenosine: roles of protein isoprenylation and carboxyl methylation reactions.

We show that both the lipopolysaccharide (LPS)-induced activation of NF-kappa DNA binding and kappa gene expression are blocked by treating murine pre-B lymphocyte 70Z/3 cells with 5'-methylthioadenosine (MTA), an inhibitor of several S-adenosylmethionine-dependent methylation reactions. We fur...

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Main Authors: Law, R E, Stimmel, J B, Damore, M A, Carter, C, Clarke, S, Wall, R
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC364073/
https://ncbi.nlm.nih.gov/pubmed/1729592
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