Lipopolysaccharide-induced NF-kappa B activation in mouse 70Z/3 pre-B lymphocytes is inhibited by mevinolin and 5'-methylthioadenosine: roles of protein isoprenylation and carboxyl methylation reactions.

We show that both the lipopolysaccharide (LPS)-induced activation of NF-kappa DNA binding and kappa gene expression are blocked by treating murine pre-B lymphocyte 70Z/3 cells with 5'-methylthioadenosine (MTA), an inhibitor of several S-adenosylmethionine-dependent methylation reactions. We further...

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הוצא לאור ב:	Mol Cell Biol
Principais autores:	Law, R E, Stimmel, J B, Damore, M A, Carter, C, Clarke, S, Wall, R
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis 1992
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1729592/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.1.103-111.1992
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