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Frizzled receptors signal through G proteins
Frizzled receptors have long been thought to couple to G proteins but biochemical evidence supporting such an interaction has been lacking. Here we expressed mammalian Wnt-Frizzled fusion proteins in Saccharomyces cerevisiae and tested the receptors’ ability to activate the yeast mitogen-activated p...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640709/ https://ncbi.nlm.nih.gov/pubmed/23524329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.03.009 |
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