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HSV-1 strain McKrae is more neuroinvasive than HSV-1 KOS after corneal or vaginal inoculation in mice

Strains of HSV-1 have been noted to vary in their pathogenesis. We compared the replication of strains KOS and McKrae in mice by two routes of infection, ocular and vaginal. Peripheral replication of KOS was similar (cornea) or attenuated over time (vagina) compared with McKrae; however, McKrae repl...

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Detalhes bibliográficos
Principais autores: Wang, Hong, Davido, David J., Morrison, Lynda A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640688/
https://ncbi.nlm.nih.gov/pubmed/23339898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.01.001
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