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Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT(1a) receptor antagonist
The α7 nicotinic acetylcholine receptor (nAChR) is highly expressed in different regions of the brain and is associated with cognitive function as well as anxiety. Agonists and positive allosteric modulators (PAMs) of the α7 subtype of nAChRs have been shown to improve cognition. Previously nicotine...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640667/ https://ncbi.nlm.nih.gov/pubmed/23321689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.01.004 |
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