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Nicotinic ACh Receptors as Therapeutic Targets in CNS Disorders

The neurotransmitter acetylcholine (ACh) can regulate neuronal excitability by acting on the cys-loop cation-conducting ligand-gated nicotinic ACh receptor channels (nAChRs). These receptors are widely distributed throughout the central nervous system, being expressed on neurons and non-neuronal cel...

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Pubblicato in:Trends Pharmacol Sci
Autori principali: Dineley, Kelly T., Pandya, Anshul A., Yakel, Jerrel L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324614/
https://ncbi.nlm.nih.gov/pubmed/25639674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2014.12.002
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