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Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice

The pathological progression of hypertrophic cardiomyopathy (HCM) is sex dimorphic such that male HCM mice develop phenotypic indicators of cardiac disease well before female HCM mice. Here, we hypothesized that alterations in myofilament function underlies, in part, this sex dimorphism in HCM disea...

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Autori principali: McKee, Laurel A.K., Chen, Hao, Regan, Jessica A., Behunin, Samantha M., Walker, Jeffery W., Walker, John S., Konhilas, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640654/
https://ncbi.nlm.nih.gov/pubmed/23352598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.12.023
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