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Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice

The pathological progression of hypertrophic cardiomyopathy (HCM) is sex dimorphic such that male HCM mice develop phenotypic indicators of cardiac disease well before female HCM mice. Here, we hypothesized that alterations in myofilament function underlies, in part, this sex dimorphism in HCM disea...

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Détails bibliographiques
Auteurs principaux: McKee, Laurel A.K., Chen, Hao, Regan, Jessica A., Behunin, Samantha M., Walker, Jeffery W., Walker, John S., Konhilas, John P.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640654/
https://ncbi.nlm.nih.gov/pubmed/23352598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.12.023
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