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Chiral Brønsted Acid Catalyzed Enantioselective Synthesis of anti-Homopropargyl Alcohols via Kinetic Resolution-Aldehyde Allenylboration Using Racemic Allenylboronates

[Image: see text] A chiral phosphoric acid catalyzed kinetic resolution/allenylboration of racemic allenylboronates with aldehydes is described. Allenylboration of aldehydes with 2.8 equivalents of allenylboronate (±)-1 in the presence of 10 mol% of catalyst (R)-2 provided anti-homopropargyl alcohol...

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Detalhes bibliográficos
Main Authors: Tsai, Andy S., Chen, Ming, Roush, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640598/
https://ncbi.nlm.nih.gov/pubmed/23484801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4003459
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